About USP <645> Water Conductivity Testing
Pharmaceutical manufacturers know that you can accurately predict the electrical conductivity of water according to ions present in a sample, which speaks to the water’s purity. Since pure water is essential in your application, you need to conduct rigorous testing to verify its suitability.
USP <645> is a standard that guides manufacturers in measuring water conductivity in sterile water and bulk water. Industries use the standard when assessing water to make sure it meets their purity standards. Typically, two types of water are tested:
- Sterile water: Sterile water for injection, sterile purified water and sterile water intended for inhalation or irrigation
- Bulk water: Steam condensate and water for hemodialysis
To achieve accurate results, we use precisely calibrated instruments. Our team measures the conductivity cell constant to an accuracy of plus or minus 2%. We can check the cell constant:
- Direct: The direct approach calls for verifying the constant by measuring a solution whose conductivity we already know.
Other factors come into play, including the water’s temperature, which affects conductivity readings.